Germline mutations and somatic mosaicism in steatotic liver diseases and related liver carcinogenesis.
Trépo E, Zucman-Rossi J, Nault JC. Nat Rev Gastroenterol Hepatol. 2026 Feb 12 Steatotic liver diseases, encompassing metabolic dysfunction-associated steatotic liver disease and alcohol-related liver disease, affect nearly one-third of the global population and are a leading cause of cirrhosis and hepatocellular carcinoma. The substantial interindividual variation in disease progression indicates important genetic contributions beyond …
